
P301S tau model
The P301S tau model is a genetically engineered mouse used in research to study Alzheimer's disease and similar neurodegenerative conditions. It carries a mutation in the tau protein gene that causes abnormal tau buildup in brain cells. This buildup leads to neuron damage, brain cell death, and cognitive decline similar to human neurodegenerative diseases. Researchers use this model to understand disease progression and test potential treatments, providing insights into how tau-related pathology affects brain function and behavior over time.