Nucleosome positioning

Nucleosome positioning refers to how DNA is arranged around protein structures called nucleosomes, which are like spools that help organize the DNA in cells. Each nucleosome consists of DNA wrapped around a core of proteins called histones. The specific placement of these nucleosomes along the DNA affects which genes are accessible for activation or suppression. Proper positioning is crucial for gene regulation, influencing cell function and development. Factors that determine nucleosome placement include DNA sequence and cellular signals, making it a dynamic process essential for healthy gene expression.