nuclear receptor coactivators

Nuclear receptor coactivators are proteins that assist nuclear receptors—specialized molecules inside cells that detect hormones like estrogen or testosterone. When these hormones bind to their receptors, coactivators help turn on specific genes by strengthening the ability of the receptors to interact with the cell's genetic material. This process influences various biological functions, including development, metabolism, and immune responses. Essentially, coactivators act as molecular partners that enhance the receptor's ability to regulate gene activity, ensuring proper cellular responses to hormonal signals.