Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB)

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) is a protein complex that plays a key role in regulating the immune response, inflammation, and cell survival. It acts as a molecular switch inside cells, turning genes on or off in response to signals like infection or stress. When activated, NF-kB moves into the cell nucleus and helps produce proteins that fight infections or promote inflammation. While essential for healthy immune defense, uncontrolled NF-kB activity can contribute to chronic inflammation and diseases such as cancer or autoimmune disorders.