NRD (Nuclear Receptor Disorder)

Nuclear Receptor Disorder (NRD) involves problems with nuclear receptors, which are specialized proteins inside cells that detect hormones like estrogen, testosterone, and thyroid hormones. These receptors help regulate gene activity and maintain bodily functions. In NRD, mutations or malfunctions in these receptors can disrupt hormone signaling, leading to issues such as hormonal imbalances, developmental abnormalities, or metabolic problems. Because nuclear receptors control many critical processes, disorders related to them can affect multiple systems, requiring diagnosis and management tailored to the specific receptor involved.