Image for Non-LTR retrotransposons

Non-LTR retrotransposons

Non-LTR retrotransposons are sequences of DNA that can copy and insert themselves into different parts of a genome without using the typical "long terminal repeat" (LTR) regions found in some transposons. They move via an RNA intermediate, where they are transcribed into RNA, then reverse-transcribed back into DNA before inserting at new locations. These elements are common in many organisms, including humans, and play a role in genome evolution and variability. Unlike some other transposons, they lack repetitive sequences at their ends, which impacts how they replicate and integrate into the DNA.