NF-kB signaling pathway

The NF-kB signaling pathway is a key mechanism in cells that helps manage immune responses, inflammation, and cell survival. When the body detects damage or infection, signals activate NF-kB, a protein that moves into the cell nucleus to turn on genes involved in defense and healing. Normally, NF-kB is kept inactive by inhibitors, but in response to specific triggers, it is released and activated. This pathway ensures that the body responds appropriately to threats, but if it’s overactive or improperly regulated, it can contribute to chronic inflammation or diseases like cancer.