NATs (N-acetyltransferases)

N-acetyltransferases (NATs) are enzymes in our bodies that help process and detoxify certain substances, including drugs and some toxins. They work by attaching an acetyl group—a small chemical piece—to these substances, making them easier for our body to eliminate. NATs play a crucial role in how quickly and effectively we clear medications and environmental chemicals, influencing individual responses to drugs and susceptibility to certain diseases. Variations in NAT activity among people can affect drug effectiveness and risk of side effects or toxicity.