Mutations in RAS genes

Mutations in RAS genes are changes in the DNA that affect a group of genes involved in controlling cell growth and division. When these mutations occur, they can lead RAS proteins to become constantly active, sending signals for cells to grow and divide uncontrollably. This abnormal behavior can contribute to the development of cancers. Essentially, RAS mutations disable normal cellular checks and balances, allowing cancer cells to proliferate unchecked. These mutations are common in various types of tumors and are a key focus for targeted cancer therapies.