MTHFR Gene

The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase, which is important for processing certain B vitamins involved in methylation, a key process in DNA creation and repair. Variations or mutations in this gene can affect enzyme activity, potentially leading to higher levels of homocysteine, an amino acid associated with increased risks of cardiovascular issues and pregnancy complications. While many people with MTHFR variants have no health problems, understanding these mutations can help guide nutritional and medical decisions to support overall health.