Michael addition

Michael addition is a chemical reaction where a molecule called a nucleophile (an electron-rich species) attaches to an unsaturated compound known as an α,β-unsaturated carbonyl. This process involves the nucleophile adding across the double bond, resulting in a new bond formation that produces a more complex molecule. It’s commonly used in organic synthesis to build substances like pharmaceuticals and natural products, allowing precise construction of complex structures through controlled chemical steps. The reaction is valued for its selectivity and efficiency in creating carbon-carbon bonds within a molecular framework.