Mendelian Randomization

Mendelian Randomization is a research method that uses genetic variations as natural experiments to explore if a specific lifestyle factor or trait, like cholesterol levels, actually causes a health outcome, such as heart disease. Since genes are randomly assigned at conception, this approach helps scientists reduce biases common in observational studies. By analyzing large genetic datasets, researchers can better determine if changing the factor might lead to better health, helping to identify potential causes of diseases and guiding prevention or treatment strategies.