Marrow Controversy

The Marrow Controversy was a 19th-century debate among scientists about whether the soft, spongy tissue inside bones (bone marrow) was responsible for producing blood cells. Some believed that marrow was the primary site of blood cell formation, while others thought the liver and spleen played that role. This debate helped scientists understand how blood is made, leading to advances in medicine and hematology. Ultimately, it was confirmed that bone marrow is the main site for producing red and white blood cells, clarifying a key aspect of human biology.