LTD (long-term depression in neurobiology)

Long-term depression (LTD) is a process in the brain where the connections between neurons become weaker over time, specifically at synapses. This weakening reduces the likelihood that one neuron will activate another in the future. LTD is thought to play a key role in fine-tuning neural circuits, helping with functions like learning, memory, and adapting by removing or weakening less-used connections. It involves changes in the strength of synaptic signals, often through modifications in receptor activity or changes in the structure of it. Overall, LTD helps balance neural activity and maintain healthy brain function.