Limb Development

Limb development is the process by which embryo tissues grow into arms and legs. It begins with the formation of limb buds, small swelling of cells on the embryo’s sides. These buds contain cells that multiply, elongate, and differentiate into bones, muscles, and skin. Signaling molecules guide this process, defining where limbs form and their future shape. The upper limbs develop first, followed by the lower limbs. Proper coordination of these signals ensures limbs develop correctly, allowing for normal movement and function after birth. Overall, limb development is a complex orchestration of cellular growth and genetic instructions guiding limb formation.