LAMP2A (Lysosome-associated membrane protein 2A)

LAMP2A (Lysosome-associated membrane protein 2A) is a specialized protein found on the membrane of lysosomes, which are cellular structures responsible for breaking down and recycling unwanted materials. LAMP2A plays a crucial role in a process called chaperone-mediated autophagy, where specific proteins are directly transported into lysosomes for degradation. It acts as a receptor, recognizing and binding these proteins to help them enter the lysosome. Proper functioning of LAMP2A is essential for cellular cleanup and maintaining cellular health, and malfunctions can be linked to certain diseases, including some neurodegenerative conditions.