
Kashin-Beck disease
Kashin-Beck disease is a chronic, deforming joint condition mainly affecting children and teenagers in certain regions of Siberia, China, and North Korea. It causes the cartilage in joints to gradually deteriorate, leading to pain, swelling, and bone deformities. The exact cause isn't fully understood, but factors like nutritional deficiencies (especially selenium and iodine), poor sanitation, and contaminated water are believed to contribute. The disease progresses slowly, resulting in reduced mobility and disability if untreated. Management includes nutritional support, physical therapy, and, in severe cases, surgery to improve function and quality of life.