Janus kinase (JAK) pathways

Janus kinase (JAK) pathways are essential communication routes inside our cells that help regulate immune responses and blood cell production. When signals like hormones or immune molecules bind to specific receptors on cell surfaces, JAK enzymes activate and trigger a cascade of events inside the cell. This process leads to the activation of a group of proteins called STATs, which then move to the cell nucleus to turn genes on or off. Overall, JAK pathways help coordinate immune defense, inflammation, and cell growth, playing a vital role in maintaining health and responding to illness.