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JAK inhibitor

JAK inhibitors are medications that block specific enzymes called Janus kinases (JAKs), which play a key role in the body's immune response by transmitting signals from various cell receptors. By inhibiting these enzymes, JAK inhibitors help reduce inflammation and immune system activity, making them effective in treating autoimmune diseases like rheumatoid arthritis, psoriasis, and certain types of blood disorders. They work orally and target the underlying immune processes rather than just treating symptoms. However, they can also suppress the immune system broadly, so their use requires careful monitoring by healthcare providers.