Itch receptors

Itch receptors are specialized nerve endings in the skin that detect stimuli causing itching sensations. When irritants like allergens, insect bites, or certain chemicals contact the skin, these receptors are activated. They send signals through nerves to the brain, which interprets them as the feeling of itch. These receptors primarily respond to histamine and other compounds involved in allergic reactions or skin irritations. Understanding how they work helps in developing treatments for itching caused by allergies, skin conditions, or insect bites.