
IDH1 (Isocitrate Dehydrogenase 1)
IDH1 (Isocitrate Dehydrogenase 1) is an enzyme involved in the body's metabolic process, specifically in cells' energy production. It helps convert a molecule called isocitrate into another called alpha-ketoglutarate, producing a small amount of energy and important molecules for cell function. In some cases, mutations in the IDH1 gene can lead to abnormal enzyme activity, which is linked to certain types of cancers, such as gliomas and acute myeloid leukemia. Understanding IDH1 helps researchers develop targeted treatments for these diseases.