Human Epidermal Growth Factor Receptor 2

Human Epidermal Growth Factor Receptor 2 (HER2) is a protein found on the surface of some cells, including those in the breast. It helps regulate cell growth and division. In some cancers, such as certain types of breast cancer, HER2 is overproduced, leading to more aggressive tumor growth. Tests are used to determine HER2 levels in tumors, which helps guide treatment options. Targeted therapies, like trastuzumab (Herceptin), can specifically attack HER2-positive cancer cells, improving treatment outcomes for patients with these aggressive cancers. Understanding HER2 status is crucial for personalized cancer care.