homology modeling

Homology modeling is a technique used in molecular biology to predict the 3D structure of a protein based on the known structures of similar proteins. Scientists start by identifying a template protein with a similar sequence and a well-determined structure. Using this template, they create a model of the target protein, filling in gaps where information is missing. This method helps researchers understand how proteins function, how they interact with other molecules, and aids in drug design by revealing potential binding sites. It’s like using a reference photo to create a new, similar piece of art.