Heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a rare immune reaction to the blood thinner heparin, where the body develops antibodies that activate platelets. This activation leads to a decrease in platelet count (thrombocytopenia) and increases the risk of abnormal blood clots forming inside blood vessels. Despite fewer platelets, there's a heightened chance of dangerous clots, which can cause serious complications like strokes or limb loss. HIT typically occurs 5-14 days after starting heparin and requires prompt diagnosis and treatment, often by stopping heparin and switching to alternative blood thinners.