guanethidine

Guanethidine is a medication used to lower high blood pressure by affecting nerve signals that control blood vessel narrowing. It works by entering nerve endings that release the chemical responsible for constricting blood vessels, gradually blocking that release. As a result, blood vessels relax and widen, helping to reduce blood pressure. Typically, it is used when other treatments haven't been effective, often under careful medical supervision, since it can cause significant side effects like low blood pressure, dizziness, or a slow heart rate.