Granulomatosis with Polyangiitis (Wegener's Granulomatosis)

Granulomatosis with polyangiitis, formerly known as Wegener's granulomatosis, is a rare autoimmune disease that causes inflammation of blood vessels (vasculitis) and leads to the formation of granulomas, which are clusters of immune cells. This condition primarily affects the respiratory system, kidneys, and sinuses, causing symptoms like nasal congestion, cough, kidney problems, and fatigue. The body’s immune system mistakenly attacks healthy tissue, resulting in damage. Treatment usually involves medications to suppress the immune response, helping to reduce inflammation and prevent complications. Early diagnosis and treatment are important for better outcomes.