Genetics of Vibratory Urticaria

Vibratory urticaria is a rare allergic reaction triggered by vibrations, such as from muscle contractions or machinery. It results in hives or welts on the skin. The condition is thought to have a genetic basis, potentially linked to mutations in specific genes that regulate how the body responds to physical stimuli. These genetic variations can affect the immune system's reaction to vibrations, causing the skin to react unusually. Understanding these genetic factors can help in diagnosing and managing the condition, providing insights into why some people experience this unique form of hives while others do not.