fugu poisoning

Fugu poisoning occurs from consuming pufferfish that contain tetrodotoxin, a potent neurotoxin. This toxin is mainly found in the fish's liver, ovaries, and skin. When ingested, tetrodotoxin blocks nerve signals, leading to paralysis, numbness, and potentially fatal respiratory failure. Despite strict preparation standards by trained chefs to remove toxic parts, accidental poisoning can still happen if the fish isn’t prepared correctly. Symptoms typically develop quickly, within a few minutes to hours, and require immediate medical attention. There is no known antidote; treatment focuses on supportive care, including respiratory support if needed.