FAD (Familial Alzheimer's disease)

Familial Alzheimer's Disease (FAD) is a rare genetic form of Alzheimer's, passed down within families. It typically manifests in individuals at an earlier age than the more common sporadic Alzheimer's, often in their 30s to mid-60s. FAD is caused by mutations in specific genes, such as APP, PSEN1, and PSEN2. While the typical Alzheimer's disease is influenced by various factors like age and lifestyle, FAD's genetic basis means that if someone has it, their children have a 50% chance of inheriting the genetic mutation and potentially developing the disease. Early diagnosis and support are crucial for those affected.