Extended-spectrum beta-lactamases (ESBLs)

Extended-spectrum beta-lactamases (ESBLs) are enzymes produced by certain bacteria that make them resistant to many commonly used antibiotics, particularly penicillins and cephalosporins. These bacteria can cause infections, making treatment more challenging. ESBLs are often found in strains of E. coli and Klebsiella, which can lead to severe illnesses, especially in hospital settings. Infections caused by ESBL-producing bacteria may require stronger, more specialized antibiotics to treat, highlighting the importance of careful antibiotic use and hygiene measures to prevent their spread.