
EP300 (E1A binding protein p300)
EP300, also known as p300, is a protein that plays a key role in controlling how genes are turned on or off in our cells. It acts as a molecular "coactivator," helping certain proteins, called transcription factors, access DNA so they can influence gene expression. p300 also has enzymatic activity that modifies other proteins, impacting various cellular processes like growth, development, and response to signals. Proper p300 function is crucial for normal cell activity, and its malfunction has been linked to diseases such as cancer and developmental disorders.