EMSA

EMSA, or Electrophoretic Mobility Shift Assay, is a laboratory technique used to study how proteins interact with DNA. In this process, a sample of DNA mixed with proteins is placed in a gel and subjected to an electric field. The proteins bind to specific DNA sequences, slowing down their movement through the gel. By analyzing the resulting patterns, researchers can determine if and how proteins interact with particular DNA segments, which is crucial for understanding gene regulation and various biological processes. It’s a valuable tool in molecular biology and biochemistry.