EGFR mutations

EGFR mutations involve changes in a gene called the epidermal growth factor receptor (EGFR), which helps regulate cell growth and division. When this gene is mutated, it can cause the receptor to become overly active, leading to uncontrolled cell growth, often seen in some cancers like non-small cell lung cancer. Identifying these mutations is important because targeted therapies, known as EGFR inhibitors, can specifically block this abnormal activity, improving treatment effectiveness. In essence, EGFR mutations are genetic changes that can drive cancer progression but also provide opportunities for targeted, personalized treatments.