DNMT3A

DNMT3A (DNA methyltransferase 3A) is an enzyme that plays a crucial role in regulating gene activity by adding methyl groups to DNA, a process known as DNA methylation. This modification influences whether genes are turned on or off, affecting cell development and function. DNMT3A is especially important during early development and in maintaining healthy blood cell production. Mutations or alterations in DNMT3A can disrupt normal gene regulation, potentially leading to disorders such as leukemia or other blood-related diseases.