Direct antiglobulin test (DAT)

The Direct Antiglobulin Test (DAT) is a blood test used to determine if a person's immune system is mistakenly attacking their own red blood cells. In this test, a small sample of blood is mixed with a solution that detects antibodies—proteins that the immune system produces against foreign substances. If antibodies are present on the red blood cells, it indicates an immune response, which can lead to conditions like hemolytic anemia. The DAT is often used in situations like blood transfusions, pregnancy, or unexplained jaundice in newborns to ensure the safety and health of the patient.