Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a protein that acts as a channel in the membranes of cells, primarily affecting organs like the lungs and pancreas. It helps regulate the movement of salt and water in and out of cells, which is crucial for producing thin, slippery mucus. In people with cystic fibrosis, a genetic mutation leads to faulty CFTR, resulting in thick, sticky mucus that can obstruct airways and lead to infections. This disrupts normal organ function and can cause serious health issues, highlighting the importance of CFTR in maintaining proper bodily fluid balance.