Cryo-electron tomography

Cryo-electron tomography is a powerful imaging technique used to visualize biological samples at very low temperatures. Scientists rapidly freeze specimens, such as cells or proteins, preserving their natural state. An electron microscope then captures a series of 2D images from different angles. These images are combined to create a detailed 3D structure of the sample. This method allows researchers to study complex biological processes and structures in their native environment, providing insights into how cells function and how diseases may develop, without the need for dyes or other treatments that could alter the sample.