Cryo-electron microscopy (Cryo-EM)

Cryo-electron microscopy (Cryo-EM) is a technique that allows scientists to visualize tiny biological molecules, like proteins and viruses, at near-atomic resolution. It involves freezing the samples rapidly to preserve their natural structure, then using powerful electron beams and advanced detectors to capture detailed images from many angles. These images are computationally combined to create detailed 3D models. Cryo-EM helps researchers understand the function of complex molecules, aiding in drug development and advancing our knowledge of biology without needing to grow crystals like in traditional methods.