Chromosomal Aberration Theory

Chromosomal Aberration Theory explains how changes in the structure or number of chromosomes can lead to genetic disorders. Chromosomes are DNA packages carrying genetic information. Sometimes, they can break, reattach incorrectly, or be gained/lost, resulting in abnormalities like deletions, duplications, or extra chromosomes. These alterations can disrupt normal development and cause health issues. The theory helps in understanding the genetic basis of various syndromes, such as Down syndrome, and highlights how chromosomal changes, rather than gene mutations alone, contribute to certain diseases and conditions.