Bruton's Tyrosine Kinase (BTK)

Bruton's Tyrosine Kinase (BTK) is an enzyme that plays a crucial role in the immune system, particularly in the development and function of B-cells, which are a type of white blood cell responsible for producing antibodies. BTK acts as a signal transducer, helping to relay messages from cell surface receptors to the inside of the cell, triggering responses essential for immune defense. Abnormalities in BTK can lead to immunodeficiency disorders, where the body struggles to fight infections, or contribute to certain types of cancers like leukemia. Medications targeting BTK are used to treat these conditions effectively.