azide nucleophiles

Azide nucleophiles are chemical species containing the azide group (N₃⁻), a linear arrangement of three nitrogen atoms carrying a negative charge. They are known for their strong nucleophilicity, meaning they readily donate electrons to other molecules during chemical reactions. Azide nucleophiles are commonly used in organic synthesis, especially in click chemistry to attach different compounds securely. Their reactivity allows them to form new bonds efficiently, making them valuable tools in creating pharmaceuticals, materials, and labeling biomolecules. Despite their usefulness, azides require careful handling due to their potential explosive nature when concentrated.