APOE ε4

APOE ε4 is a variant of the apolipoprotein E gene, which plays a role in how the body processes fats and cholesterol. Its significance is primarily linked to health risks, particularly Alzheimer's disease. Individuals carrying one or two copies of the ε4 variant have an increased likelihood of developing Alzheimer's compared to those with other variants. While not all ε4 carriers will develop the disease, it is considered a significant genetic risk factor. Understanding this helps in early detection and potential interventions for those at risk.