
Anti-HLA antibodies
Anti-HLA antibodies are proteins your immune system creates when it mistakenly recognizes certain human cell markers, called Human Leukocyte Antigens (HLA), as foreign. These antibodies can develop after exposure to foreign tissues, like through transfusions, transplants, or pregnancy. Their presence can attack transplanted organs, increasing the risk of rejection, or complicate organ donation matches. Understanding anti-HLA antibodies helps doctors assess transplant compatibility and improve outcomes by managing or reducing these immune responses.