
Amotosalen
Amotosalen is a chemical used in blood donation testing to help ensure the safety of platelets and plasma transfusions. It works by intercalating into the DNA and RNA of pathogens and white blood cells present in blood products. When exposed to UV light, Amotosalen activates and forms bonds that prevent these unwanted cells and infectious agents from multiplying, effectively inactivating them. This process reduces the risk of transmitting infections through blood transfusions, making the blood safer for recipients. It’s a crucial tool in modern blood safety protocols, especially in reducing transfusion-related infections.