Acute Graft-vs-Host Disease

Acute Graft-versus-Host Disease (GVHD) is a condition that can occur after a stem cell or bone marrow transplant, where the donated immune cells recognize the recipient’s body as foreign and attack healthy tissues. It commonly affects skin, liver, and intestines, causing symptoms like rash, jaundice, diarrhea, and abdominal pain. GVHD can range from mild to severe and requires medical management to control the immune response. This condition highlights the complex balance in transplant treatments between eliminating disease and preventing immune-related complications.