Zinc Finger Nucleases

Zinc Finger Nucleases (ZFNs) are engineered proteins that can precisely edit DNA. They consist of two parts: a zinc finger domain, which recognizes specific DNA sequences, and a nuclease enzyme that cuts the DNA at that targeted site. By designing ZFNs to target particular genes, scientists can add, delete, or modify genetic material in cells. This technology is useful in research, gene therapy, and agriculture, offering a way to correct genetic defects or improve traits with high precision. Essentially, ZFNs act as molecular scissors guided to specific DNA locations for targeted genetic manipulation.