
Yes-associated protein (YAP)
Yes-associated protein (YAP) is a key regulator in cells that influences growth, development, and tissue repair. It acts as a signaling molecule that moves into the cell nucleus to activate genes involved in cell proliferation and survival. YAP's activity is controlled by cellular signals related to the environment and cell density, helping maintain tissue balance. When functioning properly, YAP promotes healthy growth, but if its regulation is disrupted, it can contribute to cancer development by encouraging uncontrolled cell growth. Overall, YAP is essential for coordinating how cells grow and respond to their surroundings.