Wegeners granulomatosis (Granulomatosis with polyangiitis)

Wegener’s granulomatosis, now called granulomatosis with polyangiitis (GPA), is a rare autoimmune disorder where the immune system mistakenly attacks small vessels in the body, mainly affecting the respiratory tract and kidneys. This causes inflammation, leading to symptoms like sinus issues, nasal ulcers, coughing, and kidney problems. The inflammation can create granulomas—clusters of immune cells—that damage tissues. The exact cause isn’t known, but GPA is treatable with medications like immunosuppressants, which help control immune activity and prevent further damage. Early diagnosis and treatment are essential for better outcomes.