voxel-based morphometry

Voxel-based morphometry (VBM) is a neuroimaging analysis technique used to measure differences in brain structure, specifically gray matter volume, across individuals or groups. It involves taking high-resolution MRI scans, dividing the brain into tiny three-dimensional units called voxels, and then comparing their densities or volumes statistically. This process helps researchers identify areas where brain tissue may be increased, decreased, or altered due to factors like development, disease, or experience. VBM enables detailed, automated comparisons of brain anatomy, providing insights into structural brain differences in health and illness.