VIGOR trial

The VIGOR trial was a research study that tested the drug Vioxx (rofecoxib) to see if it effectively reduced pain and inflammation, particularly in patients with arthritis. It compared Vioxx to another pain reliever called naproxen. The study found that Vioxx was effective for pain relief, but later revealed that it increased the risk of heart-related problems, such as heart attacks. This trial played a key role in understanding the safety profile of Vioxx and contributed to concerns about its widespread use.